(Please see “Chronological” section under “Index” for references)
Breast cancer
12/29/2018: Efficacy of combination of panitumumab and neoadjuvant chemotherapy in HER-2 negative inflammatory breast cancer
12/23/18: Adjuvant Trastuzumab Emtansine benefits women with residual HER-2 positive breast cancer
12/16/2018: Extending adjuvant aromatase inhibitor to 10 years prolonged disease-free survival in breast cancer patients
12/15/2018: Combination of CDK4/6 inhibitor palbociclib and letrozole did not offer clinical benefit
11/18/2018: A new strategy to reduce bone metastases in breast cancer
11/4/2018: Comparison of complication rates among different techniques for breast reconstruction following mastectomy
10/27/2018: Results of the Impassion130 trial: Atezolizumab and nab-paclitaxel combination has PFS benefit in first line treatment for advanced triple-negative breast cancer.
10/20/2018: Potential benefit of anti-inflammatory therapy for lymphedema
9/23/2018: Promising results of combination therapy with Atezolizuman and nab-paclitaxel in triple-negative breast cancer
9/1/2018: Gene test can spare extended endocrine therapy in low-risk breast cancer (Poage GM et al. ASCO 2018; abstr 516)
8/26/2018: Oral Taxane showed good activity and tolerance in metastatic breast cancer
8/4/2018: A new strategy utilizing the fragile part of tumor cells to treat cancer
7/22/2018: Sentinel lymph node biopsy can be safely avoided in some breast cancer patients who received pre-operative therapy
7/15/2018: Most early breast cancer may forego chemotherapy guided by 21-gene assay
6/2/2018: Six months of adjuvant Trastuzumab is non-inferior to 12 months
5/27/2018: Wound-healing in mice triggers growth of dormant tumors
5/6/2018: Long term outcome of neoadjuvant versus post-operative chemotherapy in early breast cancer
4/29/2018: Can chemotherapy really induce metastases?
3/17/2018: Larger surgical margin width reduces local recurrence in early-stage breast cancer
2/18/2018: Consumption of ultra-processed foods and cancer risk
Lung cancer
12/9/2018: First-line atezolizumab plus chemotherapy in extensive stage small-cell lung cancer
11/11/2018: FDA approved Nivolumab in small cell lung cancer
11/10/2018: Mesothelin CAR T cell therapy in malignant pleural disease is promising
11/3/2018: ACE inhibitors and risk of lung cancer
8/5/2018: PD-1blockade before lung cancer resection
7/14/2018: Blood test to screen early stage of lung cancer with high specificity
6/24/2018: Dacomitinib improves survival in NSCLC patients with activating EGFR mutations
6/16/2018: Lorlatinib shows anti-tumor activity in ALK-positive NSCLC
6/10/2018: Immuno-chemotherapy may become the new standard for first line treatment for squamous NSCLC
6/3/2018: Immuotherapy-chemotherapy combo extends survival as first line therapy for stage IV NSCLC (non-squamous)
5/26/2018: Delay in surgery for non-small cell lung cancer can result in upstaging and prognosis
3/4/2018: Pazotanib improves PFS in extensive state small cell lung carcinoma but with toxicity
2/3/2018: Intraoperative molecular imaging helps to find more cancerous lung nodules
1/21/2018: Anti-PD-1/PD-L1 therapy and hyperprogression of advanced lung cancer
1/14/2018: ASCO practice guideline for systemic treatment of stage IV non-small cell lung cancer
Colon cancer (appendix)
9/30/2018: Mutation identified in appendiceal cancer
9/22/2018: CAR-T cell may eventually become a way of treating colorectal cancer
4/22/218: Novel combination therapy using BRAF blockage may prolong disease-free survival in metastatic colon cancer
3/10/2018: Does supplement calcium increase the risk of precancerous serrated colon polyps?
2/24/2018: Nivolumab with or without Ipilimumab improves outcomes in MSI-H metastatic colorectal cancer
2/10/2018: Colonic biofilms may contain carcinogenic bacteria
Pancreatic cancer
9/9/2018: Microbiome as potential target of treatment for pancreatic cancer
7/7/2018: Adjuvant modified FOLFIRINOX achieved significantly longer survival in resected pancreatic cancer
6/17/2018: Pre-op chemo and radiation increased overall survival in resectable pancreatic cancer
Liver cancer
7/28/2018: Death rate of liver cancer is rising quickly in the U.S.
Esophageal cancer
1/27/2018: Post-operative chemotherapy beneficial following preoperative chemoradiotherapy and resection in gastroesophageal cancer
1/20/2018: Gefitinib is active in a subgroup of advanced esophageal cancer
Gastric cancer
6/9/2018: Post-operative chemo-radiatioin does not improve survival compared with chemotherapy in gastric cancer
4/16/2018: Surgical management of gastric cancer
1/27/2018: Post-operative chemotherapy beneficial following preoperative chemoradiotherapy and resection in gastroesophageal cancer
Cholangiocarcinoma
5/10/2018: New progress in the treatment of unresectable cholangiocarcinoma
Ovarian cancer
10/6/2018: Combination of anti-PD-1 and anti CTL-4 target therapy benefited more recurrent ovarian cancer patients
9/30/2018: CT45 is a biomarker for treatment response and prognosis in ovarian cancer
9/16/2018: Bevacizumab in the Primary Treatment of Ovarian Cancer extended disease-free survival
8/19/2018: Tumor Treating Fields in combination with pacliexel raised survival in recurrent ovarian cancer patients
2/17/2018: Hyperthermic intraperitoneal chemotherapy in ovarian cancer
Uterine neoplasms
7/29/2018: Olaparib plus Vistusertib showed promise in endometrial cancer and other types of cancers
2/11/2018: Uterine neoplasms
Cervical cancer
10/28/2018: Dual stain test may guide HPV-positive women for future screening follow-ups
10/15/2018: FDA expands HPV vaccine to cover adults 27-45 years of age
8/25/2018: No Pap smear screening among some women in the new USPSTF cervical cancer guideline
Uroepithelial cancer
11/17/2018: Intravesicular installation of gemcitabine for low grade bladder cancer
5/20/2018: FDA Alert: Monotherapy with Pembrolizumab or tezolizumab in clinical trials may reduce survival among uroepithelial cancer patients with low PD-L1 expression
Prostate cancer
5/5/2018: New therapy may cause highly aggressive prostate cancer self-destruction
4/28/2018: Apalutamide delays metastasis in prostate cancer
4/1/2018: Low fat diet may enhanced drug activity of abiraterone
3/24/2018: 5α-reductase inhibitor does not increase high-grade prostate cancer
Kidney cancer
8/18/2018: Blood-based marker for early detection of kidney cancer
8/11/2018: Nivolumab plus Ipilimumab improves survival versus Sunitinib in advanced renal cell carcinoma
3/18/2018: Atezolizumab and Bevacizumab combo extends PFS in locally advanced or metastatic renal cell carcinoma
1/7/2018: Hypoxia-inducible factor-2α antagonist has activity against advanced renal cell carcinoma
Head and Neck Cancer
10/14/2018: Adding HPV vaccine to immune checkpoint inhibitor in incurable HPV19-related cancer
Melanoma
8/12/2018: Efficacy and safety of Talimogene Laherparepvec in combination with ipilimumab in advanced melanoma
5/19/2018: Beta blockers may help to improve response to immunotherapy in melanoma
Brain tumors
12/1/2018: Drug combination cleared neuroblastoma in mice
7/21/2018: Recombinant poliovirus treats glioblastoma
2/20/2018: Target therapy for brain tumors
Lymphoma
6/23/2018: Polatuzumab vedotin and bendamustine/rituximab combo improved outcome of diffuse large B-cell lymphoma
3/31/2018: Brentuximab Vedotin and chemotherapy for stage III and IV Hodgkin’s lymphoma
3/25/2018: Triple therapy effective in refractory mantle cell lymphoma
Multiple myeloma
12/30/2018: New potential drugs reverse drug resistance in multiple myeloma model
5/14/2018: Export protein inhibitor is active in refractory myeloma
Leukemia
3/11/2018: Venetoclax benefits elderly acute myeloid leukemia patients
Myelodysplastic syndrome
3/3/2018: Rigosertib used in MDS and MDS progressed to acute myeloid leukemia
Side-effects
12/22/2018: Rivaroxaban for deep vein thrombosis prevention in patients with cancer
10/20/2018: Potential benefit of anti-inflammatory therapy for lymphedema
10/7/2018: Uncommon lethal complications of immune checkpoint inhibitors
5/20/2018: FDA Alert: Monotherapy with Pembrolizumab or tezolizumab in clinical trials may reduce survival among uroepithelial cancer patients with low PD-L1 expression
1/21/2018: Anti-PD-1/PD-L1 therapy and hyperprogression of advanced lung cancer
Diagnosis
7/14/2018: Blood test to screen early stage of lung cancer with high specificity
4/21/2018: Luciferase from deep sea creature is used to determine efficacy of tumor immunotherapy
2/4/2018: Blood test for early detection of solid tumors
2/3/2018: Intraoperative molecular imaging helps to find more cancerous lung nodules
Tumor biology and novel therapeutic approach
12/8/2018: A new test can diagnose cancer in 10 minutes?
12/2/2018: New combination of immunotherapy produced response in difficult-to-treat colorectal cancer
12/1/2018: Drug combination cleared neuroblastoma in mice
11/25/2018: A more effective way to deliver drugs into the brain
11/24/2018: Identifying targets of anti-malaria drugs in treating cancer
11/18/2018: A new strategy to reduce bone metastases in breast cancer
11/10/2018: Mesothelin CAR T cell therapy in malignant pleural disease is promising
10/14/2018: Adding HPV vaccine to immune checkpoint inhibitor in incurable HPV19-related cancer
9/22/2018: CAR-T cell may eventually become a way of treating colorectal cancer
9/9/2018: Microbiome as potential target of treatment for pancreatic cancer
8/26/2018: Oral Taxane showed good activity and tolerance in metastatic breast cancer
8/4/2018: A new strategy utilizing the fragile part of tumor cells to treat cancer
7/21/2018: Recombinant poliovirus treats glioblastoma
6/30/2018: Promising drug that can “freeze” and stop the spread of cancer cells
5/19/2018: Beta blockers may help to improve response to immunotherapy in melanoma
5/5/2018: New therapy may cause highly aggressive prostate cancer self-destruction
3/3/2018: Rigosertib used in MDS and MDS progressed to acute myeloid leukemia
2/10/2018: Colonic biofilms may contain carcinogenic bacteria
2/3/2018: Intraoperative molecular imaging helps to find more cancerous lung nodules
1/28/2018: Cancer can override circadian rhythm to survive
1/13/2018: How to combat therapy-driven cancer cell growth
1/7/2018: Hypoxia-inducible factor-2α antagonist has activity against advanced renal cell carcinoma
1/1/2018: Near-infrared triggered release of cancer drugs to deliver more drugs with less side-effects
Epidemiology
11/3/2018: ACE inhibitors and risk of lung cancer
10/21/2018: FDA banned 7 ingredients found in candy, baked food, gum and beverages due to their links to cancer
7/28/2018: Death rate of liver cancer is rising quickly in the U.S.
7/8/2018: Flight attendants may have higher incidence of multiple cancers
2/18/2018: Consumption of ultra-processed foods and cancer risk
1/6/2018: Cancer death rate in the U.S. continues to decline
Prevention